# Investigational Therapy for Type 1 Diabetes **URL:** \ **Category:** T1D Tech & Daily Management Support\ **Created:** [November 16, 2023, 1:42pm UTC](https://forum.breakthrought1d.org/t/investigational-therapy-for-type-1-diabetes/73541 "2023-11-16T13:42:38Z")\ **Posts on this page:** 10\ **Page:** 1
**Author:** ![joe](https://sea1.discourse-cdn.com/flex025/user_avatar/forum.breakthrought1d.org/joe/32/2937_2.png) [@joe](https://forum.breakthrought1d.org/u/joe)\ **Post date:** [November 16, 2023, 1:42pm UTC](https://forum.breakthrought1d.org/t/investigational-therapy-for-type-1-diabetes/73541/1 "2023-11-16T13:42:38Z")
[https://264.t1dstudy.com/](https://264.t1dstudy.com/) Vertex Type 1 Clinical Study is in recruitment right now. Key innovation: this therapy does not require immunosuppressive drugs. Clearly not a cure, IMO it’s just a much better insulin pump! The VX22-264-101 Study is looking for individuals living with type 1 diabetes (T1D) to participate in a study of an investigational cell-based therapy called VX-264. VX-264 consists of cells designed to produce insulin contained within devices designed to protect the cells from the immune system. These investigational devices are implanted in the space behind the muscles of the abdominal wall. Researchers are studying the safety, tolerability, and effectiveness of VX-264 in adults with T1D and are looking to see if it could potentially reduce or eliminate the need for individuals with T1D to take insulin. ---
**Author:** ![Tlholz](https://sea1.discourse-cdn.com/flex025/user_avatar/forum.breakthrought1d.org/tlholz/32/5473_2.png) [@Tlholz](https://forum.breakthrought1d.org/u/Tlholz)\ **Post date:** [November 16, 2023, 1:52pm UTC](https://forum.breakthrought1d.org/t/investigational-therapy-for-type-1-diabetes/73541/2 "2023-11-16T13:52:21Z")
Thanks for posting this link. I saw another one and was going to sign up, but was 3 years too old to qualify. This site took my info anyway! Seems they don’t like older folks for studies as we might be more susceptible to problems or die during the period, would that it wasn’t so, I’d like to contribute… ---
**Author:** ![joe](https://sea1.discourse-cdn.com/flex025/user_avatar/forum.breakthrought1d.org/joe/32/2937_2.png) [@joe](https://forum.breakthrought1d.org/u/joe)\ **Post date:** [November 16, 2023, 3:03pm UTC](https://forum.breakthrought1d.org/t/investigational-therapy-for-type-1-diabetes/73541/3 "2023-11-16T15:03:40Z")
I think they need an age group, a location, and a specific blood type. ---
**Author:** ![joe](https://sea1.discourse-cdn.com/flex025/user_avatar/forum.breakthrought1d.org/joe/32/2937_2.png) [@joe](https://forum.breakthrought1d.org/u/joe)\ **Post date:** [November 17, 2023, 10:28pm UTC](https://forum.breakthrought1d.org/t/investigational-therapy-for-type-1-diabetes/73541/4 "2023-11-17T22:28:09Z")
I wrote to Vertex, they scheduled an interview with me on Monday December 4. I can’t believe I’m nervous. You’d think after all these years nothing could scare me! ---
**Author:** ![Jophilly](https://sea1.discourse-cdn.com/flex025/user_avatar/forum.breakthrought1d.org/jophilly/32/5473_2.png) [@Jophilly](https://forum.breakthrought1d.org/u/Jophilly)\ **Post date:** [November 19, 2023, 7:48pm UTC](https://forum.breakthrought1d.org/t/investigational-therapy-for-type-1-diabetes/73541/5 "2023-11-19T19:48:03Z")
If this works as hoped, I will absolutely consider it a cure (after 50 years as a T1D). I wish I lived near one of the testing sites, as I’d enroll. Thanks to all who do enroll !!! ---
**Author:** ![joe](https://sea1.discourse-cdn.com/flex025/user_avatar/forum.breakthrought1d.org/joe/32/2937_2.png) [@joe](https://forum.breakthrought1d.org/u/joe)\ **Post date:** [November 19, 2023, 9:21pm UTC](https://forum.breakthrought1d.org/t/investigational-therapy-for-type-1-diabetes/73541/6 "2023-11-19T21:21:45Z")
Had a very long discussion with my brother (he’s a doctor) I think it’s going to be slower than a real cure, probably missing the curve on high glycemic foods but I think it’ll be okay for mixed and low glycemic meals and I think since it’s making actual human insulin it’ll work the same way as the old cells worked and keep you from going low. Anyway I think I’m the wrong blood type but I’ll report back. ---
**Author:** ![joe](https://sea1.discourse-cdn.com/flex025/user_avatar/forum.breakthrought1d.org/joe/32/2937_2.png) [@joe](https://forum.breakthrought1d.org/u/joe)\ **Post date:** [November 20, 2023, 3:31pm UTC](https://forum.breakthrought1d.org/t/investigational-therapy-for-type-1-diabetes/73541/7 "2023-11-20T15:31:58Z")
2 posts were split to a new topic: [Joslin Medal discussion](https://forum.breakthrought1d.org/t/joslin-medal-discussion/73545) ---
**Author:** ![joe](https://sea1.discourse-cdn.com/flex025/user_avatar/forum.breakthrought1d.org/joe/32/2937_2.png) [@joe](https://forum.breakthrought1d.org/u/joe)\ **Post date:** [November 20, 2023, 3:33pm UTC](https://forum.breakthrought1d.org/t/investigational-therapy-for-type-1-diabetes/73541/8 "2023-11-20T15:33:15Z")
FYI Update The clinical trial for Vertex is for A and AB blood types ONLY! So I am eliminated. Cheers to anyone who gives it a go! ---
**Author:** ![Dennis](https://sea1.discourse-cdn.com/flex025/user_avatar/forum.breakthrought1d.org/dennis/32/5527_2.png) [@Dennis](https://forum.breakthrought1d.org/u/Dennis)\ **Post date:** [November 22, 2023, 12:32am UTC](https://forum.breakthrought1d.org/t/investigational-therapy-for-type-1-diabetes/73541/9 "2023-11-22T00:32:12Z")
The “good news” @Joe, is that you received the blood type disqualification soon after you began investigating entering the trial. Two years ago in another Vertex cell implant experiment it took much longer for my disqualification and that was after I had given access for one year to all my Dexcom data and charts. My disqualification was age, which was known from the beginning and accepted, coupled with “an unspoken” that my HbA1c was consistently 3+% too low - the implant wouldn’t show “significant improvement in A1c”. ---
**Author:** ![joe](https://sea1.discourse-cdn.com/flex025/user_avatar/forum.breakthrought1d.org/joe/32/2937_2.png) [@joe](https://forum.breakthrought1d.org/u/joe)\ **Post date:** [November 22, 2023, 1:50am UTC](https://forum.breakthrought1d.org/t/investigational-therapy-for-type-1-diabetes/73541/10 "2023-11-22T01:50:54Z")
Thanks @Dennis you are right, better sooner than later.